This maybe a duplicate of T5992 not sure. That seems to blame EFL, which I only experience this on upgrade of E. No issues with EFL 1.20.4 and E 0.21.9. I noticed this with e 22 alpha on my laptop, Intel. I also experience this on my desktop, AMD/Radeon with 22 beta. At some point GTK windows stop rendering internal contents. Further launch of the applications show an empty frame. This seems to only effect GTK, not E or EFL apps. See the following screenshots. They are only frames, and you see straight through to my desktop, purple background.
Firefox window, but only title bar renders
Leafpad, same thing, empty inside.